Leveraging Deep Stein's Unbiased Risk Estimator for Unsupervised X-ray Denoising

Abstract: Among the plethora of techniques devised to curb the prevalence of noise in medical images, deep learning based approaches have shown the most promise. However, one critical limitation of these deep learning based denoisers is the requirement of high-quality noiseless ground truth images that are difficult to obtain in many medical imaging applications such as X-rays. To circumvent this issue, we leverage recently proposed approach of [7] that incorporates Stein's Unbiased Risk Estimator (SURE) to train a deep convolutional neural network without requiring denoised ground truth X-ray data. Our experimental results demonstrate the effectiveness of SURE based approach for denoising X-ray images.