CAIPI in Practice: Towards Explainable Interactive Medical Image Classification

Abstract: Would you trust physicians if they cannot explain their decisions to you? Medical diagnostics using machine learning gained enormously in importance within the last decade. However, without further enhancements many state-of-the-art machine learning methods are not suitable for medical application. The most important reasons are insufficient data set quality and the black-box behavior of machine learning algorithms such as Deep Learning models. Consequently, end-users cannot correct the model's decisions and the corresponding explanations. The latter is crucial for the trustworthiness of machine learning in the medical domain. The research field explainable interactive machine learning searches for methods that address both shortcomings. This paper extends the explainable and interactive CAIPI algorithm and provides an interface to simplify human-in-the-loop approaches for image classification. The interface enables the end-user (1) to investigate and (2) to correct the model's prediction and explanation, and (3) to influence the data set quality. After CAIPI optimization with only a single counterexample per iteration, the model achieves an accuracy of $97.48\%$ on the Medical MNIST and $95.02\%$ on the Fashion MNIST. This accuracy is approximately equal to state-of-the-art Deep Learning optimization procedures. Besides, CAIPI reduces the labeling effort by approximately $80\%$.