Unbiased likelihood estimation of Wright-Fisher diffusion processes

Abstract: In this paper we propose a Monte Carlo maximum likelihood estimation strategy for discretely observed Wright-Fisher diffusions. Our approach provides an unbiased estimator of the likelihood function and is based on exact simulation techniques that are of special interest for diffusion processes defined on a bounded domain, where numerical methods typically fail to remain within the required boundaries. We start by building unbiased likelihood estimators for scalar diffusions and later present an extension to the multidimensional case. Consistency results of our proposed estimator are also presented and the performance of our method is illustrated through numerical examples.