Primary spray break-up from a nasal spray atomizer using Volume of Fluid to Discrete Phase Model

Abstract: Spray atomization process involves complex multi-phase phenomena. Abundant literature and validation of spray modelling for industrial applications like fuel injection in internal combustion and turbine jet engines are available. However, only a handful of studies, primarily limited to discrete phase modelling, of low-pressure applications, such as nasal spray exists. This study aims to provide insight into the external and near-nozzle spray characterization of a continuous spray and establishes good validation against the experiment. A 3-dimensional (3D) X-ray scanner was used to extract the internal nasal spray nozzle geometry which was reconstructed to build a 3D computational model. A novel volume-of-fluid to discrete phase transition model (VOF-DPM) was used to track the liquid phase and its transition to droplets, which was based on the shape and size of the liquid lumps. In this study, an early pre-stable and stable phase of spray plume development was investigated. Qualitative and quantitative analysis were carried out to validate the computational model. A liquid column exited a nozzle which distorted at its base with advancement in time and eventually formed a hollow-cone liquid sheet. It then, disintegrated due to instability that produced fluctuations to form ligaments resulting in secondary break-up. This study provides in-depth understanding of liquid jet disintegration and droplet formation, which adds value to future nasal spray device designs and techniques to facilitate more effective targeted nasal drug delivery.