GPT-Lab: Next Generation Of Optimal Chemistry Discovery By GPT Driven Robotic Lab

Abstract: The integration of robots in chemical experiments has enhanced experimental efficiency, but lacking the human intelligence to comprehend literature, they seldom provide assistance in experimental design. Therefore, achieving full-process autonomy from experiment design to validation in self-driven laboratories (SDL) remains a challenge. The introduction of Generative Pre-trained Transformers (GPT), particularly GPT-4, into robotic experimentation offers a solution. We introduce GPT-Lab, a paradigm that employs GPT models to give robots human-like intelligence. With our robotic experimentation platform, GPT-Lab mines literature for materials and methods and validates findings through high-throughput synthesis. As a demonstration, GPT-Lab analyzed 500 articles, identified 18 potential reagents, and successfully produced an accurate humidity colorimetric sensor with a root mean square error (RMSE) of 2.68%. This showcases the rapid materials discovery and validation potential of our system.