Intelligent and Miniaturized Neural Interfaces: An Emerging Era in Neurotechnology

Abstract: Integrating smart algorithms on neural devices presents significant opportunities for various brain disorders. In this paper, we review the latest advancements in the development of three categories of intelligent neural prostheses featuring embedded signal processing on the implantable or wearable device. These include: 1) Neural interfaces for closed-loop symptom tracking and responsive stimulation; 2) Neural interfaces for emerging network-related conditions, such as psychiatric disorders; and 3) Intelligent BMI SoCs for movement recovery following paralysis.