Scientific Computing with Large Language Models

Abstract: We provide an overview of the emergence of LLMs for scientific computing applications. We highlight use cases that involve natural language processing of scientific documents and specialized languages designed to describe physical systems. For the former, chatbot style applications appear in medicine, mathematics and physics and can be used iteratively with domain experts for problem solving. We also review specialized languages within molecular biology, the languages of molecules, proteins, and DNA where LLMs are being used to predict properties and even create novel physical systems at much faster rates than traditional computing methods.