A generalized software framework for consolidation of radiotherapy planning and delivery data from diverse data sources

Abstract: Aggregating large-scale radiotherapy planning and delivery data is crucial for advancing radiation oncology research and improving clinical practice, yet challenges persist due to the diversity of treatment planning systems (TPS), record and verify (R&V) systems, and complex data formats lacking standardized retrieval methods. We developed a robust software framework that automates the collection and integration of multi-institutional radiotherapy data from diverse TPS and R&V systems. By utilizing the unidirectional references of DICOM objects, our framework reconstructs complete patient datasets starting from Radiotherapy Treatment Records (RTRECORDs), managing tasks such as data queries, transfers, verification, and logging. It effectively maps DICOM linkages between RTRECORDs, RTPLANs, RTDOSEs, RTSTRUCTs, planning images, registrations, and associated diagnostic images, incorporating custom modules for data conversion and comprehensive error handling. Implemented across multiple institutions using various systems$-$ including ARIA, Eclipse, MOSAIQ, RayStation, MIM, Pinnacle$-$ the framework successfully collected data from two clinics over an 11-year period, aggregating data from 6,022 patients and 13,871 treatment plans with a success rate of 99.76% and an average processing time of approximately 18 minutes per patient. Ongoing efforts are extending data collection to clinics lacking DICOM Query/Retrieve capabilities, demonstrating the framework's adaptability to various clinical environments. This efficient automation of comprehensive data collection overcomes significant technical barriers, facilitating the creation of large-scale datasets that can accelerate advancements in radiation oncology.