Design for a Digital Twin in Clinical Patient Care

Abstract: Digital Twins hold great potential to personalize clinical patient care, provided the concept is translated to meet specific requirements dictated by established clinical workflows. We present a generalizable Digital Twin design combining knowledge graphs and ensemble learning to reflect the entire patient's clinical journey and assist clinicians in their decision-making. Such Digital Twins can be predictive, modular, evolving, informed, interpretable and explainable with applications ranging from oncology to epidemiology.