Feedback-Enhanced Online Multiple Testing with Applications to Conformal Selection

Abstract: We study online multiple testing with feedback, where decisions are made sequentially and the true state of the hypothesis is revealed after the decision has been made, either instantly or with a delay. We propose GAIF, a feedback-enhanced generalized alpha-investing framework that dynamically adjusts thresholds using revealed outcomes, ensuring finite-sample false discovery rate (FDR)/marginal FDR control. Extending GAIF to online conformal testing, we construct independent conformal $p$-values and introduce a feedback-driven model selection criterion to identify the best model/score, thereby improving statistical power. We demonstrate the effectiveness of our methods through numerical simulations and real-data applications.