Adaptive Decoding via Hierarchical Neural Information Gradients in Mouse Visual Tasks

Abstract: Understanding the encoding and decoding mechanisms of dynamic neural responses to different visual stimuli is an important topic in exploring how the brain represents visual information. Currently, hierarchically deep neural networks (DNNs) have played a significant role as tools for mining the core features of complex data. However, most methods often overlook the dynamic generation process of neural data, such as hierarchical brain's visual data, within the brain's structure. In the decoding of brain's visual data, two main paradigms are 'fine-grained decoding tests' and 'rough-grained decoding tests', which we define as focusing on a single brain region and studying the overall structure across multiple brain regions, respectively. In this paper, we mainly use the Visual Coding Neuropixel dataset from the Allen Brain Institute, and the hierarchical information extracted from some single brain regions (i.e., fine-grained decoding tests) is provided to the proposed method for studying the adaptive topological decoding between brain regions, called the Adaptive Topological Vision Transformer, or AT-ViT. In numerous experiments, the results reveal the importance of the proposed method in hierarchical networks in the visual tasks, and also validate the hypothesis that "the hierarchical information content in brain regions of the visual system can be quantified by decoding outcomes to reflect an information hierarchy." Among them, we found that neural data collected in the hippocampus can have a random decoding performance, and this negative impact on performance still holds significant scientific value.