Editing with AI: How Doctors Refine LLM-Generated Answers to Patient Queries

Abstract: Patients frequently seek information during their medical journeys, but the rising volume of digital patient messages has strained healthcare systems. LLMs offer promise in generating draft responses for clinicians, yet how physicians refine these drafts remains underexplored. We present a mixed-methods study with nine ophthalmologists answering 144 cataract surgery questions across three conditions: writing from scratch, directly editing LLM drafts, and instruction-based indirect editing. Our quantitative and qualitative analyses reveal that while LLM outputs were generally accurate, occasional errors and automation bias revealed the need for human oversight. Contextualization--adapting generic answers to local practices and patient expectations--emerged as a dominant form of editing. Editing workflows revealed trade-offs: indirect editing reduced effort but introduced errors, while direct editing ensured precision but with higher workload. We conclude with design and policy implications for building safe, scalable LLM-assisted clinical communication systems.