OmniInfer: System-Wide Acceleration Techniques for Optimizing LLM Serving Throughput and Latency

Abstract: LLMs drive a wide range of modern AI applications but impose substantial challenges on large-scale serving systems due to intensive computation, strict latency constraints, and throughput bottlenecks. We introduce OmniInfer, a unified system-level acceleration framework designed to maximize end-to-end serving efficiency through fine-grained optimization of expert placement, cache compression, and scheduling. OmniInfer integrates three complementary components: OmniPlacement for load-aware Mixture-of-Experts scheduling, OmniAttn for sparse attention acceleration, and OmniProxy for disaggregation-aware request scheduling. Built atop vLLM, OmniInfer delivers system-wide performance gains through adaptive resource disaggregation, efficient sparsity exploitation, and global coordination across prefill and decode phases. Evaluated on DeepSeek-R1 within a 10-node Ascend 910C cluster, OmniInfer achieves 616 QPM, where the unified framework reduces TPOT by 36\%, and the superimposition of OmniProxy further slashes TTFT by 38\%. The project is open-sourced at this https URL.