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W-DUALMINE: Reliability-Weighted Dual-Expert Fusion With Residual Correlation Preservation for Medical Image Fusion

Published 13 Jan 2026 in eess.IV, cs.CV, and math.NA | (2601.08920v1)

Abstract: Medical image fusion integrates complementary information from multiple imaging modalities to improve clinical interpretation. However, existing deep learningbased methods, including recent spatial-frequency frameworks such as AdaFuse and ASFE-Fusion, often suffer from a fundamental trade-off between global statistical similaritymeasured by correlation coefficient (CC) and mutual information (MI)and local structural fidelity. This paper proposes W-DUALMINE, a reliability-weighted dual-expert fusion framework designed to explicitly resolve this trade-off through architectural constraints and a theoretically grounded loss design. The proposed method introduces dense reliability maps for adaptive modality weighting, a dual-expert fusion strategy combining a global-context spatial expert and a wavelet-domain frequency expert, and a soft gradient-based arbitration mechanism. Furthermore, we employ a residual-to-average fusion paradigm that guarantees the preservation of global correlation while enhancing local details. Extensive experiments on CT-MRI, PET-MRI, and SPECT-MRI datasets demonstrate that W-DUALMINE consistently outperforms AdaFuse and ASFE-Fusion in CC and MI metrics while

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