Drivers of inter-hospital differences in intracranial EEG relative band power

Determine the specific sources of the recording hospital site effect that lead to differences in intracranial EEG relative band power across frequency bands, by identifying the technical, acquisition, and demographic factors responsible for these inter-hospital variations.

Background

The study found that recording hospital site effects explained a substantial proportion of variance in relative band power, often exceeding fixed effects such as age and sex. This effect was frequency band–specific and varied across hospitals.

The authors examined available metadata (e.g., electrode type, age range, RAM origin) and found no systematic variation explaining hospital differences. They note other potential contributors such as recording settings, electrode manufacturer, and demographic factors, but lacked sufficient metadata to test these possibilities.